International forskning

Medicinal cannabis products for the treatment of acute pain


Marco Fiore 1, Aniello Alfieri 2, Sveva Di Franco 2, Stephen Petrou 3, Giovanni Damiani 4, Maria Caterina Pace 2

  • 1Department of Women, Child and General and Specialized Surgery, University of Campania “Luigi Vanvitelli”, Naples 80138, Italy. marco.fiore@unicampania.it.
  • 2Department of Women, Child and General and Specialized Surgery, University of Campania “Luigi Vanvitelli”, Naples 80138, Italy.
  • 3Department of Emergency Medicine, University of California San Francisco, San Francisco, CA 94143, United States.
  • 4Department of Biomedical, Surgical, and Dental Sciences, University of Milan, Milan 20122, Italy.

Affiliationer

For thousands of years, medicinal cannabis has been used for pain treatment, but its use for pain management is still controversial. Meta-analysis of the literature has shown contrasting results on the addition of cannabinoids to opioids compared with placebo/other active agents to reduce pain. Clinical studies are mainly focused on medicinal cannabis use in chronic pain management, for which the analgesic effect has been proven in many studies. This review focuses on the potential use of medical cannabis for acute pain management in preclinical studies, studies on healthy subjects and the few pioneering studies in the clinical setting.